However, the anti-cancer effects …
It is one of the most available acids among phenolic acid compounds which can be naturally found in green coffee extracts and tea. It is not known, however, whether any G6PT functions are involved in tumorigenesis. The polyphenols in eggplant may help protect the body from cancer. Anti-Cancer Therapy: Chlorogenic Acid, Gallic Acid and Ellagic Acid in Synergism Archana Moon1, Trupti Agrawal2, Pooja Gupta3, Nikita Kondlekar4, Amit Taksande5 1,2,3,4,5,6(University Department of Biochemistry, RTM Nagpur University, LIT Premises, Amravati road, Nagpur-440033 Maharashtra, India) Abstract : Phytochemicals have been used as effective agents for treating illnesses.
31,54 Burgos-Morón et al suggested that CGA induced DNA damage and formed topoisomerase-DNA complexes at concentrations of 0.5 to 5 mM.
Chlorogenic acid (CHL), the most potent functional inhibitor of the microsomal glucose-6-phosphate translocase (G6PT), is thought to possess cancer chemopreventive properties.
Anthocyanins and chlorogenic acid protect cells from damage caused by free radicals. Key words: chlorogenic acid, cancer differentiation, SUMO1, c-Myc, p21 Introduction Cell differentiation is a programmed maturation of the immature stage which alters cell structure and function. Anti-HBV antigens secretion activity of chlorogenic acid, quinic acid and caffeic acid After 8 days with compound treatment, chlorogenic acid and quinic acid inhibited HBsAg secretion to some extent in HepG2.2.15 cell, but did not inhibit HBeAg secretion at a dose up to 1000 μM. Chlorogenic acid as a polyphenol has a wide range of pharmacokinetic profiles such as cancer prevention, carcinogenic, and therapeutic potential on cancer cells depending on the concentration, dose, and duration of exposure. cancer cells to differentiate, rather than killing them, could be a novel therapeutic strategy for cancer. Chlorogenic acid has been reported to have anti-proliferative activity.
Modern studies showed chlorogenic acid has the ability to induce apoptosis and cellular DNA damage in lung cancer cells without disturbing normal lung fibroblasts. [CANCER RESEARCH 48, 5941-5946, November 1, 1988] Inhibitory Effect of Curcumin, Chlorogenic Acid, Caffeic Acid, and Ferulic Acid on Tumor Promotion in Mouse Skin by 12-O-Tetradecanoylphorbol-13-acetate Mou-Tuan Huang, Robert C. Smart, Ching-Quo Wong, and Allan H. Conney Department of Chemical Biology and Pharmacognosy, College of Pharmacy, Rutgers, The State University of New …
Chlorogenic Acid (CGA, 3-CQA) is a most abundant isomer among caffeoylquinic acid isomers (3-, 4-, and 5-CQA), that currently known as 5-CQA as per guidelines of IUPAC.
Cancer. We investigated the effects of CHL and the potential role of G6PT in regulating the invasive phenotype of brain tumor-derived glioma cells.